Cystic fibrosis (CF) is a common (one affected newborn out of 2500), autosomic recessive, genetic disease in the white population and is due to mutations in the ABCC7 gene.
ABCD congratulates James E. Rothman, Randy W. Schekman and Thomas C. Südhof, Winners of the 2013 Nobel Prize in Physiology or Medicine for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells.
Endocytosis is the process used by eukaryotic cells to internalize molecules and particulate matter into vesicles.
ABCD turns thirty and we celebrated the anniversary with an international meeting that was held in Ravenna, Italy, at the Palazzo dei Congressi, from 12 to 14 September 2013.
The expressions “biological replicate” and “technical replicate” are ubiquitous in biology, but they are surprisingly recent. At first glance, the adjectives suggest that one can understand these notions in terms of a distinction between biological variation and technological variations. This however becomes problematic as soon as biological systems are used as instruments.