Two positions (one pre- and one post-doctoral fellow) are available to join the team of Prof. Letizia Lanzetti, at the Candiolo Cancer Institute starting from January 2025 The highly innovative and exciting projects concern: 1)the identification of a novel molecular mechanism responsible for sensing lipid storage and consumption in breast cancer cells 2)the role of ER to Golgi transport in the metabolic plasticity of breast cancer cells

We are looking for a highly motivated lab technician with a degree in Biology, Biotechnology, or a related field.

A Postdoctoral fellow position is available in the laboratory of “Stem cell-based functional genomics of cardiovascular disease” directed by Dr. Valentina Lo Sardo.

The European Institute of Oncology is seeking a bioinformatician in the Laboratory of Endocytosis, Signalling and Cancer, directed by Prof. Pier Paolo Di Fiore. The successful candidate will be involved in cutting-edge cancer research that integrates high-throughput and high-resolution approaches to unravel the mechanisms of carcinogenesis and metastasis. The group is strongly interested in both basic and applied cancer research.

A post-doctoral position is open in the Gabellini laboratory at San Raffaele Scientific Institute to characterize the molecular pathogenesis of acute lymphoblastic leukemia and test novel therapeutic approaches. The project will integrate manipulation of cellular and animal models with genome-wide and functional approaches.

The laboratory of Dr Ana Casañal at the Structural Biology Research Centre (SBRC) at Human Technopole (HT) is looking for a research Senior Technician/Technician https://humantechnopole.it/en/research-groups/casanal-group/. The group is focused on the structural analysis (mainly by cryo-EM) of large macromolecular complexes involved in RNA processing. In particular, the Casañal lab uses an integrated structural biology approach that combines biochemistry, biophysics, and mass- spectrometry with structural biology techniques, to elucidate the molecular mechanisms behind the addition and the regulation of biochemical marks on RNA, a process often deregulated in human disease.

We are seeking two post-docs to join our group and push forward published and unpublished work on the role of mitochondria as transducers of mechanical signals in physiology and disease. We have competitive three-year positions fully funded by AIRC and CARIPARO.

A three-year post-doctoral position funded by a MFAG AIRC is available in the laboratory of Prof. Sirio Dupont and Dr. Patrizia Romani in the Department of Molecular Medicine, University of Padova, to study the link between ferroptosis and aggressive melanoma dissemination through the blood.

The International Max Planck Research School for Living Matter (IMPRS-LM) is looking for talented and motivated PhD candidates of all nationalities with a background in MOLECULAR and CELL BIOLOGY, BIOCHEMISTRY, BIOPHYSICS, APPLIED and THEORETICAL PHYSICS, CHEMICAL BIOLOGY, STRUCTURAL BIOLOGY, SYSTEMS BIOLOGY and related fields.

Nei carcinomi mammari l’aumento dell’attività metabolica del tumore ha un valore sia prognostico, in quanto individua i tumori a decorso peggiore, sia predittivo, poiché è in grado di predire la risposta a chemioterapia neoadiuvante nei tumori appartenenti al sottotipo Triplo-negativo. Malgrado queste evidenze non esistono, al momento, marcatori metabolici in grado di rivelare i carcinomi mammari caratterizzati da elevata attività metabolica e di correlarli al rischio di recidiva o a trattamenti specifici. Recentemente, nel nostro laboratorio, sono stati identificati alcuni marcatori in grado di correlare con la prognosi delle pazienti e con lo status metabolico del loro tumore. La caratterizzazione proposta, prevede sia uno studio riguardante il loro valore predittivo di ricorrenza all’interno del sottotipo Luminale, sia uno studio molecolare e preclinico sulla loro capacità di predire la sensibilità a trattamenti mirati. Il progetto prevede, inoltre, l’opportunità di lavorare nell’ambito della ricerca oncologica secondo una visione sistemica e interdisciplinare, caratterizzata da nozioni relative a prevenzione e valorizzazione della ricerca nel campo delle biotecnologie.