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Position as Researcher available at the Department of Biosciences, University of Oslo in the research group of Professor Cinzia Progida. The position is for a period of 16 months. The candidate for this position will work on a project funded by the Norwegian Cancer Society. The goal of this project is to identify and characterize molecules and pathways involved in lysosome transformation in cancer cells, and how this is coupled with the development of the cancer cell migratory and invasive ability. Our group has access to the National imaging platform NorMIC Oslo. The Department of Biosciences harbors also an EM-lab, the Norwegian Sequencing Centre (NSC) and Proteomics services. The work includes collaboration with national and international groups and the candidate will have the possibility to spend a short visiting period in the lab of prof. Roberto Zoncu at the University of California, Berkeley.
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The focus of our lab is to unravel the molecular basis of vascular and tumor biological processes using functional genomic approaches and, if possible, try to use these genetic insights to develop novel therapeutic strategies, and translate them into novel medicine.
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The laboratory of Prof. Massimo M. Santoro at University of Padua is seeking a post-doctoral fellow to study the role of metabolism in cancer growth and spreading. Our lab has recently identified a set of novel metabolic enzymes that are crucial for the regulation of lipid metabolism and antioxidant response (Mugoni et al., Cell, Mugoni et al., Nature Protocols, Santoro, Cell Metabolism; Arslanbaeva and Santoro, Redox Biology, Facchinello et al.,Nature Metabolism, in press). Using mouse genetic approaches as well as advanced molecular and metabolic techniques we want to elucidate how lipids and metabolism regulate cancer survival and progression. Our laboratory has acquired strong experience in the field of metabolism, genetic, molecular and cellular biology working with cells and animal models.
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The Research Strategy and Communication Office supports the SR-Tiget Director in a variety of strategic and operational activities, including strategic planning, reporting, internal and external communication. The Research Strategy and Communication Officer, reporting to the Research Strategy and Communication Manager, will provide highly organized and efficient support to the Office operations with a specific focus on the production of scientific content and documents, and organization of scientific events.
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The two years curriculum of the MB4LS is designed to bridge the gap between data and discovery. MB4LS is designed to prepare young researchers to interact with the world’s most advanced biological and clinical datasets
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Avviso di selezione n° 5/AR/2021-CIR-CNRBiOmics-IBIOM-BA per il conferimento di 1 assegno di ricerca
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The aim of this project is to clarify the functional and structural relationships between respiratory complexes I and III to understand whether their supramolecular organization in supercomplexes can mitigate the effect of deleterious mutations in cytochrome b,one of the catalytic core subunits of complex III. To this purpose, biochemical approaches will be applied in human and bacterial cellular models carrying mutations in cytochrome b to analyze the structural stability and enzymatic activity of complex III in its isolated form or in assembled supercomplex I+III. The biochemical approaches will be associated with molecular dynamics simulations of supercomplex I+III by modeling wild type and mutated cytochrome b to obtain information on critical interactions between the two complexes for supercomplexes stability. From this project, we expect to obtain new knowledge on the structural and physiological relevance of supercomplexes healthy and pathological conditions.
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PhD positions are available in the course of Medical-Surgery BioTechnologies and Translational Medicine in the lab of prof. Francesca Gioia Klinger, at University of Rome Tor Vergata, Department of Biomedicine and Prevention, Section of Histology and Embryology. The research lab focus mainly on advanced techniques to protect and preserve the ovarian reserve in human and in mice models. In line with this, the research concentrate on the discovery of new molecules to be used as fertoprotective agents and the use of mesenchymal stem cells and their released factors to improve and preserve the ovarian environment
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The call for applications is open for the PhD in Molecular Biomedicine jointly offered by the Department of Life Sciences of the University of Trieste and the International Centre for Genetic Engineering and Biotechnology (ICGEB) For info please refer to the Admission section of this website where you will find links to the official announcement and info for the application the available projects Deadline June 7, 2021 @ 1 PM CE
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This new project is focusing on new regulatory mechanisms of metabolism and their relevance for cancer metastasis, funded by a Worldwide Cancer Research grant. The current research of the lab is focused on mechanotransduction and how this regulates signaling and metabolism.