We are seeking a highly motivated research scientist with previous training in cell biology and/or biochemistry for a postdoctoral position (24 months) working on "Role of (macro)autophagy in the regulation of turn-over, unconventional secretion and inter-neuronal spreading of neurodegenerative diseases- associated aggregation-prone proteins". The successful candidate will be enrolled on a funded research project aimed at identifying novel genes and signalling pathways regulating the interplay between mammalian autophagy and neurodegenerative diseases. More specifically, the project will require the use of up-to-date molecular and cellular biology techniques, such as confocal and live cell imaging, gene expression and mass spectrometry analyses, siRNA, shRNA and CRISPR/CAS9-based molecular manipulations of target gene expression, functional analyses in cell lines, patients-derived primary cells and ultimately in animal disease models, which will be deployed to analyse the contribution of the autophagic- lysosomal and unconventional secretion pathways to neurodegenerative diseases. Desired skills and experience The successful candidate should have a PhD with a solid background in molecular biology, cell biology and/or biochemistry. Research experience in molecular biology (including molecular cloning, DNA, RNA and protein manipulations) as well as an extensive experience in cell biology and cell imaging techniques are required. Additional experience in isolation and culture of primary cells, mass spectrometry and bioinformatic analyses would be considered advantageous. Interested applicants should submit a letter of application, CV and references (or informal enquiries) to: Maurizio Renna, PhD (maurizio.renna@unina.it)

Applications are invited for a temporary post of a Post-doctoral Research Fellow Level 1 within School of Medicine. Applications are invited from suitably qualified candidates for a full time fixed term position as a post-doctoral researcher working within the laboratory of Dr. Claire Robinson. The successful candidate will investigate the role of the unfolded protein response (UPR) in pancreatic cancer. The position is funded by Breakthrough Cancer Research and is for a fixed term of 24 months Project description

We are pleased to announce a stimulating opportunity for aspiring researchers (from Italy and abroad) in the field of molecular oncology. We offer a predoctoral training program designed to prepare candidates for admission to the PhD course in Molecular Medicine at the University of Torino. Successful candidate(s) will be supported by a salary throughout the beginning of the PhD Course (November 1st, 2023).

Applications are OPEN for the PhD program in Molecular Biomedicine of the University of Trieste (Dottorato in Biomedicina Molecolare dell'Università di Trieste).

These projects are part of a large collaborative network involving Research Centers and Universities in Italy and abroad.

A short term post-doctoral position is immediately available in the laboratory of prof. Licio Collavin at the University of Trieste (http://tinyurl.com/collavinlab) The lab is focused on the molecular mechanisms that determine cancer aggressiveness, with a special interest in function and regulation of the tumor suppressor DAB2IP, a Ras-GAP and signaling adaptor that modulates multiple oncogenic pathways. For more information, or to apply, feel free to write directly to prof. Collavin

The goal of our lab at the San Raffaele – Telethon institute for Gene Therapy (SR-TIGET) in Milan is to study the regulation of blood cell emergence during human embryonic development. To this aim, we use our innovative hESCs/hiPSCs platform and combine developmental cell and molecular biology to understand normal and pathological human hematopoietic development, with a particular interest in studying the genetic origins for blood disorders and developing novel strategies for their treatment.

The goal of our lab at the San Raffaele – Telethon institute for Gene Therapy (SR-TIGET) in Milan is to study the regulation of blood cell emergence during human embryonic development. To this aim, we use our innovative hESCs/hiPSCs platform and combine developmental cell and molecular biology to understand normal and pathological human hematopoietic development, with a particular interest in studying the genetic origins for blood disorders and developing novel strategies for their treatment.

A two-year post-doc position on the project entitled “The lncRNA PHOX2B-AS1 in the pathogenesis and as potential drug target in Congenital Central Hypoventilation Syndrome (CCHS)” founded by the Telethon Foundation, is available at the “Molecular Pharmacology” laboratory (PI Prof. Fornasari), Dept. of Medical Biotechnology and Translational Medicine, University of Milan.

The UCD Cancer Data lab are currently looking to recruit computational biology postdocs. We are a supportive and collaborative interdisciplinary research group based in the Conway Institute in University College Dublin. We are broadly interested in understanding how mutations in cancer alter molecular interaction networks and in identifying ways to target these alterations therapeutically. We have a particular interest in identifying genetic interactions in cancer and understanding how they influence tumour genome evolution. You can read more about areas of specific research interest here.