The Cancer Ecosystems and Metastasis Laboratory (CEMLab) at the Université Libre de Bruxelles (ULB), led by Panagiotis (Takis) Karras, is seeking motivated researchers to undertake a PhD in cancer research. The candidate will focus on a project to better characterize the drivers of cancer metastasis, profile the inter- and intra-tumor heterogeneity and plasticity combining mouse models and clinical samples. The successful applicant will join the ULB Faculty of Medicine and the Institute Jules Bordet within the campus.

Post doctoral position at Istituto Maugeri di Pavia

A postdoctoral position is open in the Gabellini laboratory at San Raffaele Scientific Institute to characterize the molecular pathogenesis of acute lymphoblastic leukemia and test novel therapeutic approaches.

Postdoctoral Researcher - Circuit Reconstruction & Regenerative Neuroscience (ERC CUSTOM_MADE) - NICO, Department of Neuroscience, University of Turin, Italy. The project aim to rebuild functional striatal circuits by grafting human striatal progenitors with optimized properties in preclinical models of Huntington’s disease, combining circuit-tracing with single-cell and spatial omics.

The successful candidate (H/F) will join Angela Taddei's team and work in close collaboration with Valérie Borde's team, both belonging to the Institut Curie Research Center and affiliated to the Nuclear Dynamics and Dynamics of Genetic Information departments respectively.

Research focuses on understanding how nuclear acyl-CoA metabolism influences chromatin remodeling and transcriptional regulation. Mitochondrial enzymes that produce acyl-CoAs, essential metabolites for chromatin modifications and gene activity, have been observed to be present and functional in the nucleus, where they generate metabolic niches that enhance local nuclear acyl-CoA synthesis, thereby impacting gene activity. This project uses omics-based approaches, metabolite tracing, proximity-labeling, and advanced imaging techniques to explore how these nuclear metabolic enzymes regulate gene expression, interact with chromatin factors, and contribute to nuclear organization and function.

A fully funded 3 years post-doctoral position is available in Terzi Lab to explore the role of a renal specific transcription factor in the progression of chronic kidney disease progression. The successful candidate will join a dynamic and collaborative team to work on cutting-edge research that has the potential to uncover new therapeutic strategies.

The LRCB (KU Leuven) is interested in studying RNA metabolism in cancer. In particular, we aim at characterising long non-coding RNAs important for cancer progression. Towards this we apply cutting edge molecular biology and biochemistry techniques coupled to in vivo and ex vivo preclinical studies, with the ultimate goal of identifying promising therapeutic targets. The laboratory hosts also Trace, a state-ofthe- art facility offering a unique collection of >150 well-annotated patient-derived models, belonging to 11 tumour types. KU Leuven is an exciting, interdisciplinary university hosting excellent facilities and research groups and providing extensive opportunities for training.

1-year postdoc position in my lab (vaccarilab.unimi.it) at the Department of Biosciences of the University of Milan. We study lysosomes and autophagy in fly models of rare disease. We use a combination of genetic, imaging and biochemical approaches and quantitative phenotypic assessments.

A Postdoctoral fellow position is available in the laboratory of “Stem cell-based functional genomics of cardiovascular disease” directed by Dr. Valentina Lo Sardo.