The Ostuni lab combines advanced single-cell and spatial genomics on human samples with mechanistic studies in the mouse to elucidate how microenvironmental factors shape the behavior of innate immune cells. Over the years, we contributed to the understanding of the molecular control and functional implications of macrophage and neutrophil diversity in homeostasis and cancer. Our research has been published in top scientific journals and is funded by the most prestigious agencies such as the European Research Council (ERC-StG, ERC-CoG, ERC-PoC). Our vision is that by taking an interdisciplinary approach to understand biology we will develop the next generation of cell and gene therapies for immune-mediated human diseases, such as cancer. In our group, wet-lab and computational scientists engage in a virtuous cycle whereby biology instructs data analysis and data analysis fuels experimental hypothesis.

Two Post-Doctoral Research Fellowships Available at the School of Medicine and Surgery of the University of Milano-Bicocca in the research group led by Emanuele Azzoni, within the framework of two exciting and ambitious projects, respectively funded by WORLDWIDE CANCER RESEARCH (WWCR) and FONDAZIONE CARIPLO/FONDAZIONE TELETHON. Both projects are aimed at understanding the role of inflammatory pathways in the context of juvenile myelomonocytic leukemia (JMML), a type of blood cancer affecting young children, for which new treatments are urgently needed.

Postdoctoral positions are immediately available in the Laboratory of Muscle Stem Cells and Gene Regulation (LMSCGR) at NIAMS of the National Institutes of Health, Bethesda, MD, USA. Ambitious and strongly motivated individuals with a solid background in molecular biology (bioinformatics is desirable but not required) are invited to apply. The main areas of investigations relate to: 1)Intersection of metabolism and epigenetics in the regulation of skeletal muscle stem cell biology 2)Role of chromatin- and histone-modifying protein complexes in embryonic and muscle stem cells

IFOM just opened multiple positions for tenure-track PIs and Head of Facility. As we are now expanding our teams and programs, we are seeking passionate scientists who share our vision and are committed to making a difference in basic, translational and clinical cancer research.

Two research fellowships are open in the Ghigna laboratory at the Institute of Molecular Genetics Luigi Luca Cavalli-Sforza of the National Research Council (IGM-CNR). We have an extensive experience in the study of post-transcriptional regulation of gene expression and how it impinges on key physiological and pathological conditions, including cancer.