The European Institute of Oncology (IEO) is seeking a bioinformatician in the Laboratory of Endocytosis, Signalling and Cancer, directed by Prof. Pier Paolo Di Fiore, with a 12-month, potentially renewable, contract. The successful candidate will support activities related to the project entitled “An integrated nanophotonics-multiomics platform for the stratification of breast cancer patients for diagnostic purposes” (code: PNRR-MCNT2-2023-12378490 - codice CUP: J43C24000470006), Principal Investigator – Prof. Pier Paolo Di Fiore, funded by the National Recovery and Resilience Plan (PNRR) of the Italian Ministry of Health.

The successful candidate will be involved in cutting-edge cancer research that integrates high-throughput and high-resolution approaches to unravel the mechanisms of carcinogenesis and metastasis. The group is strongly interested in both basic and applied cancer research.

The major areas of interest are:

- Stem cells in cancer and metastasis;

- Regulation of cell logistics in cancer and metastasis;

- Metabolic alterations in cancer and metastasis.

The successful candidate will work on research projects with a strong focus on data analysis and interpretation from experimental datasets, such as genomic, proteomic, and transcriptomic datasets, as well as clinical datasets. The successful candidates will also engage in data mining from cancer databases and public repositories of scientific datasets to contribute to impactful cancer research. The successful candidate will be expected to interact with the wet-lab extensively and proactively.

KEY RESPONSIBILITIES:

• Analyze, integrate, and interpret large-scale multi-omics datasets (genomic, proteomic, transcriptomic) and clinical data.
• Perform data mining on cancer-related databases and publicly available datasets.
• Collaborate with team members to design and execute computational workflows for cancer research.
• Contribute to manuscript preparation and scientific presentations.
• Present findings at international conferences and collaborate with external partners on high-profile projects.

QUALIFICATIONS:

• PhD in Bioinformatics, Computational Biology, or a related field;
• Strong background in bioinformatics, genomics, and large-scale data analysis;
• Proficiency in programming languages such as Python and/or R;
• Strong communication skills and proficiency in written and spoken English;
• Experience with cancer research and familiarity with cancer databases is desirable;
• Experience with HPC and pipeline manager tools (NextFlow, Snakemake) is a plus;
• Previous experience in working with clinical datasets is a plus;
• Excellent problem-solving skills and the ability to work independently and as part of a team is a plus.

WHAT WE OFFER:

• A dynamic and collaborative research environment at one of Europe’s leading cancer research institutes.
• Opportunity to work on high-impact international research projects.
• Access to cutting-edge computational resources and state-of-the-art experimental data.
• Competitive salary and benefits package, commensurate to the qualifications.
• Smart working, compatibly with the scientific needs of the projects.

CONTRACT TYPE AND SALARY

Contract type and salary will be commiserate with the candidate’s experience.

APPLICATION DEADLINES AND MODALITIES

Applications for participation in the selection must be received no later than 12.00 noon on Novembre, 30^th via the appropriate link.

The application must contain:

- a detailed and updated CV, dated and signed, certifying training and professional activities, with specific authorization to process personal data pursuant to art. 13 of GDPR 679/16;

- any document or declaration useful for the assessment by the Examination Board.

- name and contact details of at least two references.

The European Institute of Oncology accepts no responsibility for the non-receipt of applications by the deadline, for which the date of receipt shall be considered the official date of receipt.

Only applications complete with the required documentation and sent according to the indicated procedure will be taken into consideration.

SELECTION AND EVALUATION PROCEDURE

The identification of the fellow will take place through a comparative evaluation of the candidates based on qualifications and a possible oral interview.

The assessment will consist of an evaluation of the candidate's CV, aimed at ascertaining the required knowledge and skills necessary for the performance of the activities involved in the above-mentioned project.

The oral interview, if any, will be aimed at examining in-depth the candidate's educational and professional experiences, personal motivations and aptitudes, as well as assessing the candidate's availability for multidisciplinary activities and technical-scientific discussions. Failure to attend the interview, for any reason whatsoever, will be considered as renouncement of the selection.

PROCESSING OF PERSONAL DATA

The personal data, compulsorily provided, will be processed in compliance with Legislative Decree no. 101 of 10 August 2018, which adapts the Personal Data Protection Code (Legislative Decree no. 196 of 30 June 2003) to the provisions of Regulation (EU) 2016/679, and only for the fulfilments related to this procedure and for those consequent to the possible establishment of the working relationship, according to what is also provided for in the privacy policy, which must be accepted by each candidate at the time of sending his/her application.

EQUAL OPPORTUNITIES

This notice is issued in compliance with equal opportunities between men and women for access to employment and economic treatment, pursuant to Legislative Decree no. 198/2006. 3

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This notice is published on the website of the Research Area of the European Institute of Oncology https://www.research.ieo.it/careers-and-jobs/.