Cell Biology of Disease
An overview and representation of basic discoveries stemming from medical needs and potentially leading to therapeutic applications
Pier Paolo Di Fiore's lecture was part of a Course held for graduate students in the Cell and Molecular biology track of San Raffaele University during the summer of 2014. Aim of this Course was to provide examples of how unsolved health needs in clinical medicine can lead to major basic discoveries that in turn provide insights into novel therapeutic approaches. This process is commonly referred to as "translational" research. This workshop, however, placed emphasis on the basic biological processes unveiled through in-depth dissection of ill-defined etiological or pathogenic issues in diseases as diverse as cancer, periodic fever and muscular dystrophy.