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23 February 2022

Why do many cancer patients develop delayed metastases? How do metastatic cells survive in a foreign environment? Can we identify disseminated cancer cells before metastatic outgrowth? If you are interested in answering these questions, Montagner lab is looking for two creative, independent, and ambitious Postdocs. Our mission is to identify innovative actionable targets to kill disseminated metastatic cells before the onset of metastasis. In our lab we apply bulk (qPCR, western blotting, cytofluorimetry) and single cell analyses (scRNAseq,immunofluorescence, multispectral imaging, mass cytometry) which encompass a breadth of disciplines (molecular biology, biochemistry, mechanobiology, bioinformatics, optogenetics) spanning diverse areas (cell biology, genomics, and metabolomics, pre-clinical translation, liquid biopsies). The Postdocs will isolate disseminated cells from multiple sources and animal models, generate single cell expression profiles, characterize the microenvironment, develop organotypic systems in vitro and design experiments for orthogonal validation or functional studies (patient-derived cell lines, high content screens, animal models) using technologies available through our group and our collaborators.(Montagner et al., Nature Cell Biology 2020; Zangrossi et al., Cancers 2021; Zangrossi et al., Cancers 2021).

23 February 2022

Interested in understanding how blood cells form? A postdoctoral position is available in the laboratory of Dr. Andrea Ditadi at SR-TIGET (Telethon Institute for Gene Therapy at the Ospedale San Raffaele) in Milan to study new layers of regulation of blood development.