The project a project aims at: 1. the clarification of the PZ mechanism of action as a tool to identify potential new targets; 2. the screening of FDA approved orphan drugs to hit the TZ identified molecular targets. The candidate will acquire experience in cell and molecular biology, advanced imaging approaches and high throughput screening technologies.

The Vienna Biocenter (VBC) PhD Programme in Life Sciences has been successfully running since 1993, providing students from all over the world with exceptional training. As a student at the VBC PhD Programme you will be supervised by a top scientist and have full access to state-of-the-art facilities, thus giving you an opportunity to launch a successful scientific career.

As an IPP student, your PhD research will be conducted within the lab of one of the participating groups. The Group Leader in whose lab you are based will act as your mentor and provide advice and guidance to ensure that you receive training in both the scientific skills and the creative and critical thinking abilities that you will need for your research and personal development as a scientist.

The Career Development Award consists of three-to-five years of funding allocated to an independent investigator at a host institute in Italy

Anna Kajaste's group is interested in studying the molecular mechanisms of host-vector interplay in the context of hematopoietic stem cell gene therapy of monogenic inflammatory diseases, with particular focus on innate immunity and host responses to transduction.