A postdoctoral position is available in the newly established RNA Biology of the Neuron unit directed by Dr. Jean-Michel Cioni at the San Raffaele Institute, Milan.

The main focus of our research is to understand the molecular basis underlying mRNA trafficking and translation in neuronal compartments, and how dysregulation of these processes leads to neurological disorders. In particular, the postdoctoral researcher will investigate the roles of membrane trafficking in the control of local protein synthesis in axons and the associated functions in vivo. This project will require the combination of biochemistry, genome-wide analysis (RNAseq) and cutting-edge imaging approaches in diverse animal models (Xenopus and mice) and cell culture systems.

We are seeking for a highly motivated candidate with strong interest in neuroscience and experience in cellular biology, RNA biology, protein biochemistry and general molecular biology. The candidate will be required to plan and carry out experiments independently as well as assisting other researchers to foster the laboratory’s research output.

This is a three years position funded by a Giovanni Armenise - Harvard Foundation Award with the possibility to start from September 2019.

Interested candidates should email a detailed CV and contacts of referees to Dr. Jean-Michel Cioni; email: cioni.jeanmichel@hsr.it

Specific references:

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons. Cell 176, 56-72 e15 (2019).
Molecular control of local translation in axon development and maintenance. Curr Opin Neurobiol 51, 86-94 (2018).