Postdoctoral Fellow

MRC Centre for Developmental Neurobiology

King’s College London

Summary

Applications are invited for a postdoctoral position in the Makeyev lab at MRC Centre of Developmental Neurobiology, King’s College London (http://www.kcl.ac.uk/ioppn/depts/devneuro/Research/groups/makeyev.aspx). The project will aim to understand how coupling between alternative splicing and RNA quality control mechanisms (e.g. see Genes Dev. 2012, 26:1209-1223 or PLoS? Genet. 2014, 10:e1004771) contributes to nervous system development and function. The position is available immediately and supported by a 3-year BBSRC grant.

Requirements

The successful candidate will have a recent Ph.D. in life sciences along with a strong publication record including at least one first-author paper published in a high-impact journal and ideally other publications documenting scientific productivity. Due to multidisciplinary nature of this program, substantial expertise in PCR, qPCR, molecular cloning, site-directed mutagenesis, preparing RNA probes /in vitro/, /in vitro/ splicing assays, RNA gel shift assays, immunoblotting, immunofluorescence, culturing and transfecting mammalian cell lines and lentiviral transduction will be essential. Background in bioinformatics (e.g. analysing next-generation sequencing data) or/and image processing (e.g., ImageJ or Matlab) will be an advantage. Applicant should be able to work independently and as a part of a research team and have effective communication skills.

The project will be carried out at the MRC Centre of Developmental Neurobiology, King’s College London (New Hunt’s House, Guy’s Campus). The Centre is located in Central London and provides an excellent intellectual environment and state-of-the-art facilities.

For informal inquiries, please contact Eugene Makeyev (e-mail: eugene.makeyev@kcl.ac.uk).

Salary: Basic annual starting salary will be in the range of £31,644 to £37,756, plus London allowance of £2,323 p.a., depending on skills and experience.

Duration: This full-time post is expected to start on October 1 2015.