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2 Post-doctoral positions in Juan S. Bonifacino's lab at NIH.
Location
National Institutes of Health (NIH), Bethesda (USA)
Host Lab
The John Edward Porter Neuroscience Research Center
Contract Duration
Salary
Deadline for application
 

2 post-doctoral positions are available in Prof. Juan S. Bonifacino's laboratory at the US National Institutes of Health (NIH) that will become available on October 1, 2015. Candidates must have a Ph.D., M.D. or equivalent degree, and no more than five years of research experience since receipt of their doctoral degree.Prof. Bonifacino is particularly interested in candidates with expertise in neurobiology, including experience working with neurons in primary culture or transgenic mouse models. Candidates with other types of expertise, including molecular biology, biochemistry, and fluorescence microscopy and imaging are also welcome to apply as long as they are exceptionally talented, motivated and willing to learn.

Candidates should submit a message with an attached CV to bonifacinoj@helix.nih.gov.

Bonifacino's lab works on the molecular mechanisms of protein trafficking, with a more recent focus on the mechanisms of polarized sorting in neurons and the mechanisms of organelle positioning and motility. Below are references to some recent publications:

BORC, a Multisubunit Complex that Regulates Lysosome Positioning.
Pu J, Schindler C, Jia R, Jarnik M, Backlund P, Bonifacino JS
Dev Cell. 2015, in press
 
EARP is a multisubunit tethering complex involved in endocytic recycling.
Schindler C, Chen Y, Pu J, Guo X, Bonifacino JS.
Nat Cell Biol. 2015 Mar 23. doi: 10.1038/ncb3129. [Epub ahead of print]
PMID: 25799061
 
Adaptor proteins involved in polarized sorting.
Bonifacino JS.
J Cell Biol. 2014 Jan 6;204(1):7-17. doi: 10.1083/jcb.201310021. Review.
PMID: 24395635
 
The adaptor protein-1 μ1B subunit expands the repertoire of basolateral sorting signal recognition in epithelial cells.
Guo X, Mattera R, Ren X, Chen Y, Retamal C, González A, Bonifacino JS.
Dev Cell. 2013 Nov 11;27(3):353-66. doi: 10.1016/j.devcel.2013.10.006.
PMID: 24229647
 
Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1.
Ren X, Farías GG, Canagarajah BJ, Bonifacino JS, Hurley JH.
Cell. 2013 Feb 14;152(4):755-67. doi: 10.1016/j.cell.2012.12.042.
PMID: 23415225
 
Signal-mediated, AP-1/clathrin-dependent sorting of transmembrane receptors to the somatodendritic domain of hippocampal neurons.
Farías GG, Cuitino L, Guo X, Ren X, Jarnik M, Mattera R, Bonifacino JS.
Neuron. 2012 Sep 6;75(5):810-23. doi: 10.1016/j.neuron.2012.07.007.
PMID: 22958822

Prof. Bonifacino lab is locate here:
http://www.nih.gov/about/porter/index.htm

 

Information about post-doctoral training at the NIH can be found at this link:
https://www.training.nih.gov/programs/postdoc_irp