A 4 year post-doc will address the hypothesis that early changes in axonal biology, and particularly in RNA localization and axonal signalling, play a role in ALS. The project will use a recently generated mouse model of ALS, microfluidic chambers to isolate axons, and a novel RNA tagging tool. This project is based in UCL ION within Gipi Schiavo's lab.

post-doc that will focus on the in vivo isolation and analysis of cell specific and subcellular RNA changes in motor neurons of a novel ALS mouse model. This will be achieved using a novel RNA tagging system in mice. The work will be carried out in UCL ION with Lizzy Fisher.

Premio per una pubblicazione internazionale nelle scienze biomediche, apparsa su una rivista con alto fattore di impatto (IF >10)

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A project aimed at the characterization of new antagonists for the treatment of neurodegenerative pathologies by using extracellular electrophysiology