Two positions (one pre- and one post-doctoral fellow) are available to join the team of Prof. Letizia Lanzetti, at the Candiolo Cancer Institute starting from January 2025 The highly innovative and exciting projects concern: 1)the identification of a novel molecular mechanism responsible for sensing lipid storage and consumption in breast cancer cells 2)the role of ER to Golgi transport in the metabolic plasticity of breast cancer cells

A Bioinformatician position is available in the Group of Cardiac Development, Remodeling and Regeneration under the supervision of Dr. Paola Cattaneo. The group is part of the University of Milan a center of Excellence and one of the biggest University in Italy and is located at the Monzino Cardiology Center in Milan, Italy. Further information at www.cattaneo-cardiolab.com

A 16 months fellowship (“assegno di ricerca”) is available at IEO and UPO (Universita’ del Piemonte Orientale) starting from July 2024, in the lab of Prof. Giuliana Pelicci, for research work on the epigenetic profiling in liquid biopsy for personalized medicine in meningioma patients, in the context of a PRIN research project in collaboration with Bonaldi group and Istituto Neurologico Besta (Prof. Di Meco). The position will be assigned through a ministerial competition: you can find all details on how to apply in the attached document and at the link: https://www.uniupo.it/it/ricerca/assegni-di-ricerca/bandi-assegni-di-ricerca/bando-dr-n-4742024-id-509

Defilippi’s lab will offer to the applicant all the conditions to carry out her/his work, with innovative techniques in a centre which benefit of the facilities required to carry on the proposed research, including fully equipped cell culture, microscope and animal facility.

The UCD Cancer Data lab are currently looking to recruit computational biology postdocs. We are a supportive and collaborative interdisciplinary research group based in the Conway Institute in University College Dublin. We are broadly interested in understanding how mutations in cancer alter molecular interaction networks and in identifying ways to target these alterations therapeutically. We have a particular interest in identifying genetic interactions in cancer and understanding how they influence tumour genome evolution. You can read more about areas of specific research interest here.

Are you an ambitious MSc or PhD student seeking a challenge at the forefront of genomics, computational biology and RNA therapeutics?

The “Unit of Pathogenesis and Treatment of Immune and Bone Diseases” lab, led by Anna Villa at the San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), Milan, Italy is recruiting a talented and motivated research fellow. The project will be focused on the study of ectopic bone marrow niche and optimization of innovative gene correction platform. The research activities of our laboratory are focused on the study of pathological mechanisms of immune and bone diseases and the preclinical evaluation of innovative therapeutic approaches based on gene therapy and novel conditioning regimens. As part of the SR-TIGET, a world-leading Institute in the field of gene and cell therapy for the treatment of human genetic diseases, we benefit from a highly competitive, international and scientifically stimulating environment and offer excellent state-of-the-art facilities and infrastructures, and access to clinically relevant human samples.

Position as Researcher available at the Department of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo. The position is for a period of 3 years. The candidate will generate and analyze new, cutting-edge high-throughput sequencing data of three-dimensional (3D) genome reorganization during nuclear deformations. The goal is to unravel new mechano-transduction pathways linked to 3D genome reorganization in cancer. The candidate for this position will work on a project funded by the Norwegian Cancer Society. The work will be carried out in a cross-disciplinary collaboration between the research groups of Associate Professor Jonas Paulsen and Prof. Cinzia Progida. Building on bioinformatics software developed in Paulsen research group [Nature Protoc. 2018; Nature Genetics 2019], the data will be used to generate predictive computational models of 3D genome deformation and gene expression changes during different types of nuclear deformations. Imaging techniques, including super-resolution imaging, will be used to validate the models. The Department of Biosciences has access to state-of-the-art infrastructure, including a High-throughput sequencing facility (Norwegian Sequencing Centre), as well as an imaging facility (NorMIC)

We have discovered that cancers increase the production/accumulation of abnormal ncRNA, which activate the RNA sensing pathway in cells of the tumor microenvironment through extracellular vesicles (tEVs), (Biagini et al., submitted). The project, funded by AIRC (www.airc.it/english), aims at characterizing the effects of the RNA sensing pathway in tumors and associated immune cells using cell type specific approaches. We will identify the endogenous RNA species involved in signaling to the RNA sensing pathway, and the biogenesis of these ncRNA cargos in tEVs. We have fully funded post-doc and pre-doc/PhD positions to investigate the roles of the RNA sensing pathway in tumor progression and metastasis formation and identify drugs modulating this process.

Position as Researcher available at the Department of Biosciences, University of Oslo in the research group of Professor Cinzia Progida. The position is for a period of 16 months. The candidate for this position will work on a project funded by the Norwegian Cancer Society. The goal of this project is to identify and characterize molecules and pathways involved in lysosome transformation in cancer cells, and how this is coupled with the development of the cancer cell migratory and invasive ability. Our group has access to the National imaging platform NorMIC Oslo. The Department of Biosciences harbors also an EM-lab, the Norwegian Sequencing Centre (NSC) and Proteomics services. The work includes collaboration with national and international groups and the candidate will have the possibility to spend a short visiting period in the lab of prof. Roberto Zoncu at the University of California, Berkeley.