The ubiquitin system is fundamental to virtually all biological processes and is essential for maintaining cellular and organismal homeostasis. Recent technological advances are revealing new roles for specialized ubiquitin signals, including understudied chain types and ubiquitin-like proteins, and how these post-translational modifications regulate diverse cellular functions. Dysregulation or pathogen-mediated hijacking of Ub/UBL pathways is increasingly recognized as a driver of disease, and both academic and industry researchers are now intensively targeting Ub/UBL pathways for therapeutic intervention.

This EMBO Workshop will cover the latest developments in understanding how Ub and UBLs contribute to diverse biological pathways, with a focus on mechanistic insights and disease-associated perturbations, and will showcase opportunities at the interface of basic biology and translation.

The primary goals of this EMBO Workshop are to:

1. Present cutting-edge discoveries and novel methodologies in the Ub/UBL field.
2. Bridge basic mechanistic research with translational applications and discuss the challenges of harnessing Ub/Ubl pathways for therapeutic applications.
3. Foster cross-disciplinary collaborations between established researchers and trainees by facilitating interaction and discussion.

For more information: https://meetings.embo.org/event/26-ubiquitin