This position is part of a 5-year ERC funded research project aiming to get fundamenta insights into how signaling inputs orchestrate changes in chromatin and transcriptional activity of targets in gene regulatory networks (GRNs) that control progenitor/stem cell proliferation and fates during organogenesis. The position is available in the Developmental Genetics Group at the Department Biomedicine of the University of Basel, Switzerland.

Tasks include:

1. Computational analysis of large-scale biological datasets that include comparative transcriptome analyses (RNA-Seq) and their integration with chromatin and epigenetic datasets (ChIP-Seq, 4C, Hi-Seq, ATAC-Seq).

2. Analysis and functional interpretation of the datasets generated (de novo motif discovery, pathway analyses) in close interaction with experimentalists in the group.

3. In silico simulations and analyses of GRNs. A fascinating aspect of our research is to understand how these robust GRNs were altered during vertebrate limb evolution and diversification. Part of this research will be done together with collaborating groups.

Further details can be found in the attached advert.